According to the Wikipedia, Physiologically based pharmacokinetic modelling could be defined as "a mathematical modeling technique for predicting the absorption, distribution, metabolism and excretion (ADME) of synthetic or natural chemical substances in humans and other animal species". As the Wiki describe the methods, the modelling method can predict or describe ADME of a chemical or substances in more physiological manner.
As I like to make a web-based program, I have coded the published model of my friends (Jeong et al.).
There are many limits on the page, but you can see a prototype of PBPK program. Go to https://misol.kr/labs/PBPK.html .